Former basketball star Lamar Odom, the estranged husband of reality TV star Khloe Kardashian, had used cocaine and herbal Viagra before he was found unresponsive in a brothel, according to 911 calls released by police.
He was taken to hospital on Tuesday after being found by staff at the Love Ranch legal brothel in Crystal, Nevada.
Odom had been using cocaine on Saturday and had taken as many as 10 performance-enhancing tablets in the three days before he collapsed, employees at the brothel told emergency services.
Kardashian and her sisters Kim and Kourtney, her mother Kris Jenner and half-sister Kendall Jenner are all reportedly at his bedside at Sunrise Hospital in Las Vegas.
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On Wednesday, Kendall tweeted: "Please don't go."
Nye County Sheriff Sharon Wehrly said on Wednesday that a worker at the legal brothel reported Odom was found unresponsive with blood coming from his nose and mouth.
Nevada authorities have taken a blood sample to establish if there was anything in his body.
US media report that although Kardashian filed for divorce in 2013, it had yet to be processed and she was making decisions about his medical care.